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A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer.
Fantini D, Glaser AP, Rimar KJ, Wang Y, Schipma M, Varghese N, Rademaker A, Behdad A, Yellapa A, Yu Y, Sze CC, Wang L, Zhao Z, Crawford SE, Hu D, Licht JD, Collings CK, Bartom E, Theodorescu D, Shilatifard A, Meeks JJ. Fantini D, et al. Oncogene. 2018 Apr;37(14):1911-1925. doi: 10.1038/s41388-017-0099-6. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367767 Free PMC article.
A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.
Morgan MAJ, Rickels RA, Collings CK, He X, Cao K, Herz HM, Cozzolino KA, Abshiru NA, Marshall SA, Rendleman EJ, Sze CC, Piunti A, Kelleher NL, Savas JN, Shilatifard A. Morgan MAJ, et al. Among authors: sze cc. Genes Dev. 2017 Oct 1;31(19):2003-2014. doi: 10.1101/gad.305201.117. Genes Dev. 2017. PMID: 29089422 Free PMC article.
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.
Douillet D, Sze CC, Ryan C, Piunti A, Shah AP, Ugarenko M, Marshall SA, Rendleman EJ, Zha D, Helmin KA, Zhao Z, Cao K, Morgan MA, Singer BD, Bartom ET, Smith ER, Shilatifard A. Douillet D, et al. Among authors: sze cc. Nat Genet. 2020 Jun;52(6):615-625. doi: 10.1038/s41588-020-0618-1. Epub 2020 May 11. Nat Genet. 2020. PMID: 32393859 Free PMC article.
Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.
Rickels R, Herz HM, Sze CC, Cao K, Morgan MA, Collings CK, Gause M, Takahashi YH, Wang L, Rendleman EJ, Marshall SA, Krueger A, Bartom ET, Piunti A, Smith ER, Abshiru NA, Kelleher NL, Dorsett D, Shilatifard A. Rickels R, et al. Among authors: sze cc. Nat Genet. 2017 Nov;49(11):1647-1653. doi: 10.1038/ng.3965. Epub 2017 Oct 2. Nat Genet. 2017. PMID: 28967912 Free PMC article.
12 results